CEFIDEROCOL: A TROJAN HORSE FOR THE MANAGEMENT OF MULTIDRUG-RESISTANT ENTEROBACTERALES IN A TERTIARY CARE HOSPITAL IN PAKISTAN

Authors

  • Amnah Nasrullah Department of Pathology, Pak Emirates Military Hospital/National University of Medical Sciences Rawalpindi
  • Nadia Tayyab Department of Pathology, Combined Military Hospital, Quetta
  • Warda Furqan Department of Pathology, Pak Emirates Military Hospital/National University of Medical Sciences Rawalpindi
  • Sana Hussain Rehman College of Allied Health sciences, Rehman Medical Institute Peshawar
  • Sidra Naveed Department of Pathology, Pak Emirates Military Hospital/National University of Medical Sciences Rawalpindi
  • Faisal Hanif Department of Pathology, Pak Emirates Military Hospital/National University of Medical Sciences Rawalpindi
  • Javaid Usman Department of Microbiology, Army Medical College/National University of Medical Sciences Rawalpindi

Keywords:

Antibiotic, Cefiderocol, Bacteria, Enterobacterales, Pathology

Abstract

Objective: To assess the efficacy of cefiderocol in patients with multidrug-resistant enterobacterales.

Material & Methods: A research study was carried out at Clinical Pathology Laboratory, Pak Emirates Military Hospital (PEMH) Rawalpindi, Pakistan (National University of Medical Sciences).  This study was completed in 6 months from June 2021 to November 2021. Data was analyzed by SPSS version 21.

Results: One hundred and fifty-eight (158) samples of blood, pus, body fluids, urine, and lower respiratory tract aspirates were analyzed. Mueller Hinton Agar (MHA) was used for antimicrobial susceptibility testing for all antimicrobials. Colistin agar was used for Polymyxin E testing. Clinical and Laboratory Standards Institute 2021(CLSI) was followed for result interpretation, among 158 MDR enterobacterales, 154 were sensitive to cefiderocol. 

Conclusion: Cefiderocol came out to be the most active among all the tested antimicrobials. It had good efficacy against MDR Enterobacterales. 

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Published

2022-12-31

How to Cite

Nasrullah, A., Tayyab, N., Furqan, W., Hussain, S., Naveed, S., Hanif, F., & Usman, J. (2022). CEFIDEROCOL: A TROJAN HORSE FOR THE MANAGEMENT OF MULTIDRUG-RESISTANT ENTEROBACTERALES IN A TERTIARY CARE HOSPITAL IN PAKISTAN. Annals of Allied Health Sciences, 8(2), 40–44. Retrieved from http://aahs.kmu.edu.pk/index.php/aahs/article/view/210

Issue

Vol. 8 No. 2 (2022): Annals of Allied Health Sciences

Section

Articles

License

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/.

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