Evaluation of soluble transferrin receptors and ferritin level patients of βeta thalassemia major

Authors

  • Muhammad Asif Zeb
  • Nargis Yousif Baqai

Keywords:

soluble transferrin receptors, ferritin, beta thalassemia major, patient

Abstract

Aim: The purpose of this study was to evaluate sTfR and ferritin level in beta thalassemia major for diagnosis and management of iron chelating therapy.

Materials and methods: This study was conducted on 400 samples from β thalassemia major patients. ELISA technique was used for the detection of serum ferritin and sTfR according to the manufacturer’s instructions.

Results: In male beta thalassemia major patients sTfR level was 89.2±20.1 nmol/l while in female patients mean sTfR was 97.4±23.3 nmol/l which were high on comparing with control. Serum ferritin level in male patient was 3013.35±914.08 ng/ml while in female patients was 3213.43±1014.08 ng/ml.

Conclusion: The concentration of sTfR, and ferritin level was increased in beta thalassemia major patients which indicate increased marrow activity and increased body iron.

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Published

2017-01-01

How to Cite

Zeb, M. A., & Baqai, N. Y. (2017). Evaluation of soluble transferrin receptors and ferritin level patients of βeta thalassemia major. Annals of Allied Health Sciences, 3(1), 14–16. Retrieved from http://aahs.kmu.edu.pk/index.php/aahs/article/view/41

Issue

Vol. 3 No. 1 (2017): Annals of Allied Health Sciences

Section

Articles

License

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/.

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