ANTIBIOTIC SUSCEPTIBILITY PATTERN OF URINARY TRACT PATHOGENS ISOLATED AT A TERTIARY CARE HOSPITAL IN PESHAWAR
Keywords:Antibiotic, Bacteria, Infection, Pathogens, Urinary
Objective: The current descriptive cross-sectional study was conducted to determine the sensitivity pattern of uropathogen against commonly used antibiotics in a tertiary care hospital of district Peshawar.
Material & Methods: A total of 100 urine specimens were consecutively collected from suspect of urinary tract infection, both male and female, in a sterile container. All the specimens were inoculated on Cystine lysine electrolyte deficient agar and uropathogen were identified by using colonial morphology and different biochemical tests. Antibiotic susceptibility pattern was determined by disc diffusion method according to the protocol of Clinical and laboratory standard institute.
Results: Out of 100 urine specimens 5 different uropathogen were isolated encompassing E. coli, S. aureus, Enterobacter spp., P. aeruginosa, and E. faecalis. The frequency of UTI was more common in female than male patient and in age groups of 16-30 and 46-60 years. Imipenem and Nitrofurantoin were found to be the most sensitive antibiotic for gram-negative and gram-positive uropathogen respectively.
Conclusion: The present study reveals that E. coli is the most frequent uropathogen in Hayatabad Medical Complex, Peshawar. The antibiotic susceptibility pattern indicates that the isolated uropathogen show significant resistant to commonly used antibiotics.
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